HFpEF Pharmacotherapy: What a Network Meta-analysis Compared

This network meta-analysis compared established and emerging pharmacotherapies evaluated in randomised trials of heart failure with preserved ejection fraction (HFpEF).

This network meta-analysis compared established and emerging pharmacotherapies evaluated in randomised trials of heart failure with preserved ejection fraction (HFpEF).

DAPA ACT HF-TIMI 68 tested in-hospital initiation of dapagliflozin 10 mg daily in 2,401 patients hospitalised for heart failure.
FAIR-HF2 evaluated the efficacy and safety of intravenous ferric carboxymaltose in people with heart failure, left ventricular ejection fraction of 45% or less and iron deficiency.
SUMMIT enrolled 731 people with HFpEF and obesity to compare tirzepatide with placebo for at least 52 weeks.
This FINEARTS-HF analysis examined finerenone in people with heart failure and left ventricular ejection fraction of at least 40%, according to how recently a worsening heart failure event…